I remember reading a book—no, a series—in the early 90s or so. The clearest memory I have is that there was some sort of drug that made anyone who took it “perfect”—healthy, beautiful, athletic, etc. It was also addictive after just one dose, and there was no way to get off it—to stop taking it meant death. The main character’s wife was dosed with it so that the suppliers could control the hero. I think the protagonist was white, and seem to recall that his wife was described as having an Afro. I think it may have been by Jack Chalker?
Does that trigger any memories for anyone?