What Was the Name of That Book?

I remem­ber read­ing a book – no, a series – in the early 90s or so. The clear­est mem­ory I have is that there was some sort of drug that made any­one who took it “perfect” – healthy, beau­ti­ful, ath­letic, etc. It was also addic­tive after just one dose, and there was no way to get off it – to stop tak­ing it meant death. The main character’s wife was dosed with it so that the sup­pli­ers could con­trol the hero. I think the pro­tag­o­nist was white, and seem to recall that his wife was described as hav­ing an Afro.

Does that trig­ger any mem­o­ries for anyone?

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